The return leg will be played at Ajax's Johan Cruyff Arena on May 8.
Tottenham Hotspur striker Harry Kane's determination to prove his doubters wrong after a slow start to the campaign has driven the England international to the top of the scoring charts in a remarkable season for the player and his club.
Two goals from Marcos Alonso gave Chelsea a 2-1 victory over Tottenham Hotspur on Sunday in the first-ever Premier League game at Wembley Stadium.
Manchester City climbed back into the Premier League's top four as second-half goals by Phil Foden, Julian Alvarez and Bernardo Silva sealed a comeback 3-1 victory at Everton on Wednesday.
The Copa del Rey semi-final draw will be made on Friday.
IMAGES from the English Premier League matches played on Sunday.
English Premier League club Sunderland have appointed Gustavo Poyet as manager on Tuesday. The 45 year-old has agreed a two year contract at the Stadium of Light and will take charge of the Black Cats with immediate effect.
IMAGES from the English Premier League matches played on Saturday.
A summary of Sunday's action in the Premier League.
Manchester United were denied by a spirited Stoke City performance as Joe Allen pounced late to secure the visitors their first point at Old Trafford since 1989 in a deserved 1-1 Premier League draw.
A round-up of Saturday's action in the Premier League.
Rashford put United ahead in the seventh minute
Tottenham Hotspur have reached agreement with the FA to host Champions League games at Wembley next season with an option to use the national stadium for all matches in the 2017-18 campaign while they are building a new ground. "Having Tottenham at Wembley for big European nights next season is a welcome opportunity for us to further the stadium's position as a world-class venue," FA chief executive Martin Glenn said in a joint statement with Spurs on Saturday. Tottenham are redeveloping White Hart Lane by building a 400 million pounds ($584.92 million) 61,000-seater stadium next to their existing ground and will have a reduced capacity next term as a result. They will use Wembley to meet UEFA requirements. "Given the current reduction in capacity at White Hart Lane for next season and the ticketing requirements for (the) Champions League, playing at Wembley will mean that we can continue to accommodate all of our existing season ticket holders," Tottenham chairman Daniel Levy said.
IMAGES from the EPL matches played on Sunday.
The 58-year-old pointed to the 26-point gap in the Premier League table between runners-up Liverpool and his fourth-placed former team as evidence of a massive gulf between the sides.
Seven-time European champions AC Milan hit back from two goals down against Celtic to claim a 4-2 victory that sent them into the Europa League knockout phase on Thursday as they were among 14 teams to progress in Europe's second-tier competition.
Tottenham Hotspur's England duo Harry Kane and Dele Alli fired them to a comfortable 2-0 win over mid-table Watford that cemented their place in the top four at Wembley on Monday.
Mourinho's side failed to turn their domination into more goals and things got edgy late on when Saville's shot evaded Gazzaniga who seemed slow to get down.
IMAGES from the English Premier League matches played on Saturday.
Liverpool strolled to a 2-0 victory over Brentford, while Newcastle drew 1-1 at Bournemouth.
Arsenal claimed their first Premier League win at Everton for six years as Leandro Trossard's second-half strike proved enough to secure the points at Goodison Park on Sunday.
Thierry Henry salvaged a 1-1 draw for Arsenal against Tottenham Hotspur in a final north London derby
Llorente's second-half treble, a double from Son Heung-min and a late effort from Kyle Walker-Peters in driving snow at a freezing Wembley Stadium settled an game where tensions had threatened to bubble over before the break.
A summary of Saturday's action in the Premier League.
A last-minute own goal gave Liverpool a 2-1 win over Tottenham Hotspur to keep them top of the Premier League but Manchester City stayed two points behind having won at Fulham. Huddersfield Town were relegated after their defeat by Crystal Palace.
Fourth-tier Newport County stunned former FA Cup winners Leeds United with a last-gasp 2-1 win in the third round to spark a joyous pitch invasion at their Rodney Parade ground on Sunday.
There is still a long way to go, with a young Ajax side sure to present a formidable obstacle to a Spurs squad shorn of leading strikers Harry Kane and Son Heung-min.
The quarter-final draw was the last in the current format with UEFA adopting an all-new format from the 2024-25 season onwards.
Leicester City said they had a request to postpone Thursday's game against Tottenham Hotspur rejected by the league.
Images from the English Premier League matches played on Wednesday night.
Arsenal ruthlessly exploited Emmanuel Adebayor's moment of madness to come from behind and beat Tottenham Hotspur 5-2 in another eventful north London derby.
Images from the English Premier League matches played on Sunday
Arsenal needed a late equaliser from Theo Walcott to salvage a 1-1 draw against arch-rivals Tottenham Hotspur in the League Cup semi-final.
Arsenal goalkeeper Petr Cech will be out for three to four weeks with the calf injury he picked up in Wednesday's Premier League defeat by Swansea City, manager Arsene Wenger has said.
Tottenham Hotspur scored three late goals to beat Bolton Wanderers on Tuesday and set up an FA Cup semi-final against Chelsea, after replaying the game that was abandoned when midfielder Fabrice Muamba suffered a cardiac arrest on the pitch.
A student who mocked footballer Fabrice Muamba on Twitter after the Bolton Wanderers midfielder collapsed during a match was jailed on Tuesday for inciting racial hatred.
News of all that's transpired on and off the football field
Kingsley Coman came back to haunt Paris St Germain again as he earned Bayern Munich a 1-0 win in their Champions League last-16 first leg in Paris on Tuesday.
Liverpool took a giant step towards their first title since 1990 on Saturday when their 3-0 win at Bournemouth combined with Manchester United's 2-1 victory at Manchester City to leave the champions 14 points adrift of the Premier League leaders.
There were renewed calls for action against racism in Italian football on Friday after Inter Milan fans were accused of abusing Tottenham Hotspur striker Emmanuel Adebayor in a Europa League last 16 clash in the San Siro.
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